凤丹籽饼粕单萜苷类成分的研究

刘普,李亮,邓瑞雪,卢宗元,尹卫平

中国药学杂志 ›› 2013, Vol. 48 ›› Issue (17) : 1445-1448.

中国药学杂志 ›› 2013, Vol. 48 ›› Issue (17) : 1445-1448. DOI: 10.11669/cpj.2013.17.006
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凤丹籽饼粕单萜苷类成分的研究

  • 刘普,李亮,邓瑞雪,卢宗元,尹卫平
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Monoterpene Glucosides in Seed Cakes of Paeonia ostii

  • LIU Pu,LI Liang,DENG Rui-xue,LU Zong-yuan,YIN Wei-ping
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摘要

目的研究凤丹籽饼粕的化学成分。方法采用硅胶柱色谱、ToyopearlHW-40、SephadexLH-20等多种柱色谱分离,制备高效液相色谱对有效部位进行分离、纯化,根据波谱数据分析鉴定化合物结构。结果从牡丹籽饼粕的正丁醇层分离得到7个单萜苷类化合物,分别鉴定为芍药苷(paeoniflorin,Ⅰ),氧化芍药苷(oxypaeoniflorin,Ⅱ),白芍苷(abiflofin,Ⅲ),4″-羟基白芍苷(4″-hydroxyl-albiflorinⅣ),牡丹酮-1-O-β-D-吡喃葡萄糖苷(1-O-β-D-glucopyransoyl-paeonisuffron,Ⅴ),β-gentiobiosyl-paeoniflorin(Ⅵ),白芍苷R1(abiflofinR1,Ⅶ)。结论所有化合物均为首次从凤丹种子及凤丹中分离得到的化合物。

Abstract

OBJECTIVE To study the chemical constituents of the seed cakes of Paeonia ostii. METHODS Chemical constituents were isolated by Toyopearl HW-40,Sephadex LH-20,preparative HPLC,and silica gel column chromatographies. The structures were elucidated on the basis of spectral data analysis. RESULTS Seven monoterpene glucosides,paeoniflorin(Ⅰ),oxypaeoniflorin(Ⅱ),abiflofin(Ⅲ),4″- hydroxylalbiflorin(Ⅳ),1-O-β-D-glucopyransoylpaeonisuffron(Ⅴ),β-gentiobi-osylpaeoniflorin(Ⅵ),and abiflofin R1(Ⅶ)were isolated from the seed cake of Paeonia ostii. CONCLUSION All the compounds are isolated from the seed cakes of Paeonia ostii for the first time.

关键词

凤丹 / 籽饼粕 / 化学成分 / 单萜苷类化合物 / 芍药苷 / 白芍苷

Key words

Paeonia ostii / seed cake / chemical constituent / monoterpene glucosides / paeoniflorin / abiflofin

引用本文

导出引用
刘普,李亮,邓瑞雪,卢宗元,尹卫平. 凤丹籽饼粕单萜苷类成分的研究[J]. 中国药学杂志, 2013, 48(17): 1445-1448 https://doi.org/10.11669/cpj.2013.17.006
LIU Pu,LI Liang,DENG Rui-xue,LU Zong-yuan,YIN Wei-ping. Monoterpene Glucosides in Seed Cakes of Paeonia ostii[J]. Chinese Pharmaceutical Journal, 2013, 48(17): 1445-1448 https://doi.org/10.11669/cpj.2013.17.006
中图分类号: R284   

参考文献

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